Dynaverse.net
Off Topic => Engineering => Topic started by: Nemesis on February 19, 2007, 10:55:36 pm
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Link 1 (http://www.muhc.ca/media/news/?ItemID=23909)
The 120 scientists involved in the AGP leveraged the unprecedented statistical power generated by this unique sample set by using “gene chip” technology to look for genetic commonality in autistic individuals from almost 1,200 families. The researchers also scanned DNA from these families for genetic mutations known as copy number variations (CNV), or sub-microscopic genomic insertions and deletions, that scientists believe might be involved with this and other common diseases.
“The phase one results published today reveal new genetic mutations associated with autism that were previously unknown,” says Dr Fombonne, a McGill University professor of psychiatry. “Specifically, the findings implicate a previously unidentified region of chromosome 11 that has been associated with brain development.”
The study also highlights a special group of nerve cells, called glutamate neurons, and the genes affecting their development and function, suggesting they play a critical role in autism spectrum disorders.
Link 2 (http://www.nj.com/printer/printer.ssf?/base/news-11/117177694297300.xml&coll=1)
The UMDNJ researchers say they have found that children with autism are unable to metabolize key fatty acids that help the body fight inflammation that causes damage to the brain and other organs.
"It's an exciting story that's unfolding," said George Lambert, coordinator of the 15-member research team.
The potential treatment, members of the team say, is a kind of "therapeutic cocktail" tailored to each child, which would give them a dose of a "good" fatty acid that they are not able to make on their own. Team member Bernd Spur of UMDNJ-Stratford created the chemical process to replicate one of those good fatty acids.
"The pathway doesn't work (in the body), so we circumvent it," said Spur, a chemist.
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Nemisis, thanks for posting this. Our old Friend Ron (Dallas) has a son (Monkey boy) , who has Autism. I'll be giving him a call later on telling him about this. I also know a great couple in England, Chug (Gary and Julie) from another forum who has a son with this problem.
Stephen
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I knew that there was a forum member who once mentioned autism in connection with a family member but I couldn't remember who so I posted it hoping he or she would see it and find it useful. Glad to know that it is being passed on.