At the moment, not really. Mojang ... er... I mean Microsoft... kinda went about killing off the modding community by discontinuing support for the Bukkit community, all because they were just about to release a MOD API based on the work that the Bukkit staff did for so many months. Then they never released it.
You can check out what they still have working at bukkit.org Some still work, some you have to back up to a previous version (at least they were smart enough to allow for that) of Minecraft to get to work. Now note that most of these are for servers, but can be used Single Player side as well.
I haven't touched Minecraft in about 7 months, I used to be on it daily for at least an hour, but the direction they took it was just disappointing to put it mildly. The kids still love it, and I'll play with them on the Xbox when they want, but I haven't touched the PC version in a long time.