Ahh ok, I see what you mean.
There was a few series that almost had what it needed in that vein, Consider Earth 2 for example. The basic over all plot of the show was pretty darn good for the most part, and given the cast, they came across as seasoned, even though many of them didn't have much time on the screen prior.
Or better yet, and I know I'm dating myself here, How about something like Space:1999 , of course we would have to change the name, and uhm probably the location, as the moon itself would not fly with our modern audience. But perhaps a small rogue planet, or asteroid. you could build a lot of tension with the right writers.
I think the hard part, is having the depiction of maturity ,that we saw in ST6, without the fun we had watching the frivolity of the cast in the past.
Stephen