I've seen a bit of it. I can't actually think of anyone I know (outside these forums) who has gone to Vista. There seems to be a lot more resistance to Vista than any prior form of Windows (even Win ME).
I've been using Vista Ultimate x64 for quite a while now...
Outside Dominion Wars, Birth of the Federation, ST: Hidden Evil and the SFC II game titles, all my software works on Vista..
Busines apps, PSP Photo X2, Adobe CS3, Flash Player 10, MS Office 2008, IE 8, and many many games, including BF 1942, NWN with all expansions, Hellgate London, Crysis, Tron 2.0, Max Payne 1 & 2 (though I did have to recompile the sound for Max Payne 1, but that took all of 2 min with the included tools), Armada, Armada II, Elite Force 1 and 2, Splinter Cell, KOTOR and KOTOR II (KOTOR II needed the MSS32.dll from KOTOR I to prevent random crashes), Sins of a Solar Empire, Jedi Knight II : Outcast, and several other titles.. all currently installed on this rig and all under Vista..
I have this rig dual booting for XP just so I can play SFC II titles on the Dyna, BOTF, Dominion Wars and Hidden Evil.
I can play Single player and GSA and TCP/IP on the SFC II Titles under Vista without a problem. Also the server kit runs great under Vista as well.