I just posted this over in Jack's "Kill All Spammers" thread in Ten Forward and I thought others might be interested and miss it there. I have eliminated all spam from my personal Email (Comcast POP mail)... Not just filtered it out where it still comes in but is deleted before I see it, either; I mean gone gone gone! - I just do not receive spam any more. (well, maybe one or two messages per week tops)
I did this with a combination of Mailwasher program from Firetrust ($25 registration fee with internet discount code) and the free Spamcop.net service.
Mailwasher allows me to view my mailbox out there in Comcast-Land before downloading messages to Outlook Express. From there I can forward spam messages to Spamcop.net with only two clicks. The only issue with the system is that I then had to go to the Spamcop.net web-site and submit each message individually. Not time consuming, but I think most end-users would not bother with the two-step process...
Anyway, Spamcop.net then deals with the actual originating network of the spam, the ISP hosting that network, and whoever the 'money trail' in the spam points to and demands that they all cease and desist. It didn't happen overnight, but I went from an average of 6 ~ 10 spam messages per day to about 1 per week.
It's a beautiful thing!