Malak, I'm assuming you fly Klingon going from your pic. Once the D5s are out, fly them. Far better arcs and power curve than the D7s.
Drone defence: fly a bit faster than the drones (obviously this excludes fast ones - see later), and manuever so that the droner doesn't cross your T. You want to be flying parallel to the droner, so that you can use your dissies and ph1s to keep hitting him at range 8.99 or less, constantly. Turn off your phaser point defence; don't need it if you're going faster (plus youhave AMD). Continue to do this till you either run him out of drones (at which point he'll run to the border), or you do enough internals so that he can't keep speed up to be able to escape.
A tip for using dissies in a D5 hull. Turn one pair off and overload the other pair - more accuracy for the same damage and power usage as for 4 standards. Also, once the D5L is out, get in that. It's a great droner killer.
For fast drones, make sure you're in a ship that can do speed 31. Fast drones are speed 32, and have 3 turns duration. As long as you stay outside of range 3, they can't hit you. The rest of the above tactics are valid.