A simple reason not to take meds is simply that depression is a much more complicated condition than can be addressed by medication. Even if we were to assume that depression is totally dependent on only an insufficient amount of seratonin at synapses, these meds are like swatting flies with a shotgun. There is no possible way to target some "correct" level of seratonin. The problem would more likely be more systemic and complex than parts per billion at synapses.
From personal experience I have to disagree with you 100%. A few weeks ago I was in a very bad way. Now I can lead a somewhat normal life, hopefully to get better. For you to advise someone to forgo medication prescribed by a medical professional is very irresponsible.
You have some very scientific lingo there, have you ever suffered from depression? Do you have an alternative to taking meds? Maybe "suck it up and quit feeling sorry for yourself"? or "it's just a phase you are going through"?
Speaking for myself, 7 weeks ago I was going to take my own life, or someone else's. Manic depression. I've had it all my life, recognized the signs and got help. Part of that was medication. I'm alive, four fortunate souls who happened to be around when I was at my lowest moment are alive.
How dare you be so arrogant to tell someone not to take medication, because you don't believe it does any good?
Manic-depression is signficantly different from situational depression which I would assume that J'inn would be suffering from at this point in his life. You should certainly be on meds if you are a danger to others or yourself. In fact, if you are, have been, or continue to be suicidal, you should be under observation. Bipolar disorder is indeed a lifelong problem but situational depression is not and you may be surprised to know that bipolar disorder can be treated with a completely different set of medication than is depression in general. Those most efficacious often retard seratonin at synapses rather than enhance it as do MAOs, although I may be misremembering this as it has been some time since I looked at these issues.
There is a general trend in this society to medicate problems, Viagra, Ritalin, Zoloft, etc, etc, rather than address the root cause of disease. Situational depression would be much more effectively handled by the "talking cure" than popping Zoloft. And just for your information, I happen to have a degree in psychology, so I feel that gives me some room to speak. I am not a licensed physician but anyone that is functional enough to seek help, write a comedic piece about it, and is likely suffering from a situational depression due to a tramatic life event is certainly not a candidate for medication in my book.
By the way, I am glad you are feeling better and that you got the help you needed.