whoops...hehe...your right about the crew part...I was getting my ships mixed up. (A future Warp 1 refit of the Liberty had a crew of 60...not the original) Permanant Crew would be 16. (she could handle up to 40 on her grav deck if need be, more if they dont mind spending most of the trip in zero-g or under acceleration gravity)
As for Weapons, sure Laser Cannons are not the hard kill type yet, but these would be one of the last things added to the ship, five years from now. If we still don't have the hard kill lasers by then, a small naval gun is not all that hard to construct, and in some ways, could possibly work better than a Laser. Conventional Missiles are a must, If for whatever reason a Nuke is needed (Armageddon type situation), it can be shipped up to the ship.