Disruptors with a speed of 2000, which is ten times the default tactical warp speed, are effective against warping targets.
I tried to destroy a Klingon Battlestation in a light cruiser via the brilliant warp flyby tactic. It's an easy task against speed-650 bolts. I cannot easily win if the base has speed-2000 bolts. The damage on bare hull adds up, just as it does when facing Fed, Rom, and Borg bases.
0x0001DF1D is the address of the little-endian float variable for internal Disruptor Bolt speed.
Default bytes are 00 20 CB 45 (6500.0f).
I recommend 00 40 9C 46 (20000.0f).
Klingon planets, ships, and bases will no longer be extremely easy to defeat with warp strafing.
The other races can easily hit warping targets with Phasers, R-Disruptors, and Cutting Beams. The Klingons (or any race that uses Disruptor primary weapons) can do that too with faster Disruptor Bolt speed.