If I hadn't already built my system last summer I would have waited for the BTX myself. It's going to be much quieter than the current form factor. The only two things I would be worried about are: 1. That I haven't seen any CD/DVD drives for the S-ATA come out yet. I'd by one for my current system if I could find one. 2. There doesn't seem to be any backwards compatibility for PS-2, P-ATA, or the 3.5" floppy drive for the BTX that are still used as main stream devices. Transferring information to your new BTX system will be much harder because of the lack of P-ATA unless you already use S-ATA. Sure you can spend $40~$60USD on some type of data mover or just spend $8~$10 on a loop back network cable but that can be a pain. They should have left one P-ATA connector for just such an occurrence. Or in lack of that create a P-ATA connector adapter for the PCI-Express slot.
After I loaded my OS onto my new system I tried to move all the data from my old machine to the new one. I couldn't use a loop-back network cable because my network card on my old Dell died. So I had to pull the hard drive and attach it to the new system directly. I could do that because I had a P-ATA connectors on my new system. Had my new system been a BTX machine I would have been stuck. One other thing I should mention as well, with the lack of P-ATA and a 3.5" floppy drive Win98/se is going to be dead in the water. So if your new system is going to be a BTX form factor, make sure you have at least Win2000 on hand when you make the switch. Just my 2 cents worth on this subject, hope this helps.