I have encountered the F1 bug, but not since the Beta patch, so perhaps there's hope. In any case, you have two choices. You can either quit the game and restart (and hope the problem fixes itself, which it usually does), or if you really need to get into F1 mode, you can hit the ESC key, go into the Options menu, and choose it there. This probably wouldn't work on multiplayer - never tried using ESC in multi.
The voices bug happens to me when the game crashes. Here is the easy fix:
Go to your sfc.ini file, open it with Notepad or Wordpad. Find the value for "voices," and set it to "voices=3" (instead of "voices=0," which is what it seems to change to when you have certain kinds of crashes). This will start the voices back up again, and you don't have to go through the tedious re-installing business.